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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TSHZ3 All Species: 33.33
Human Site: S417 Identified Species: 81.48
UniProt: Q63HK5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q63HK5 NP_065907.2 1081 118566 S417 H F I K V T N S A M K K G K P
Chimpanzee Pan troglodytes XP_512561 1070 117230 S406 H F I K V T N S A M K K G K P
Rhesus Macaque Macaca mulatta XP_001103809 1081 118554 S417 H F I K V T N S A M K K G K P
Dog Lupus familis XP_541721 1137 124213 S473 H F I K V T N S A M K K G K P
Cat Felis silvestris
Mouse Mus musculus Q8CGV9 1081 118608 S417 H F I K V T N S A M K K G K P
Rat Rattus norvegicus NP_001100976 1038 113807 T391 T P V T P T I T T L L D E K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508239 1194 130249 S530 H F I K V T N S A M K K G K P
Chicken Gallus gallus XP_414125 1073 117771 S411 H F I K V T N S A M K K G K P
Frog Xenopus laevis NP_001090569 1004 110567 A357 K G K S V L E A P A T P T S L
Zebra Danio Brachydanio rerio XP_694172 1191 130444 S490 H F I K V T N S A I K K G K P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 99.4 89.1 N.A. 95.1 91.8 N.A. 83.5 90.9 81.4 68.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 99.6 91.8 N.A. 97.6 93.5 N.A. 86.9 95 86.8 78.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 6.6 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 100 100 13.3 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 80 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % E
% Phe: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 0 80 0 0 % G
% His: 80 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 80 0 0 0 10 0 0 10 0 0 0 0 0 % I
% Lys: 10 0 10 80 0 0 0 0 0 0 80 80 0 90 0 % K
% Leu: 0 0 0 0 0 10 0 0 0 10 10 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 10 0 0 0 10 0 0 10 0 0 80 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 80 0 0 0 0 0 10 0 % S
% Thr: 10 0 0 10 0 90 0 10 10 0 10 0 10 0 0 % T
% Val: 0 0 10 0 90 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _